This formula's own materials use this specific framing: what they call the "Trinity of Nerve Discomfort" — impaired signaling, poor circulation, and oxidative stress — worth understanding exactly what each piece refers to.
Impaired nerve signaling, poor circulation to peripheral tissues, and oxidative stress are named as the three connected pieces this formula's own materials describe addressing together, rather than targeting one single cause.
"Trinity" is this formula's own branding term for a three-ingredient-category approach — worth reading it as a memorable organizing framework for the ingredient list, not as an independently established clinical model.